What is BioTE® DIM? The Top 5 Reasons Why You Need To Start DIM Today?

Dr. Joseph Pazona, Board Certified Urologist

86% of Americans take nutritional supplements. The most commonly purchased over-the-counter supplements are vitamins and minerals which we learned (and forgot) about in biology. Then, you have all of the “Super Beta X” (insert your favorite male organ) supplements from infomercials.

But what if I told you that, potentially, the most powerful supplement was something you never heard of?

Would you like to be leaner, stronger, feel better, and fight cancer?

If the answer is “yes”, then BioTE® DIM SGS+ might be right for you.

Let’s dive into the what, how, and why of BioTE® DIM SGS+, including the top 5 benefits you may see when you start DIM today.

What is BioTE® DIM SGS+?

A proprietary formulation developed for BioTE® by Thorne Research, DIM SGS+ contains:

  • Diindolymethane (DIM)
  • Sulforaphane
  • Pomegranate extract (ellagic acid)

DIM stands for diindolylmethane (don’t worry, I can’t pronounce it either). DIM is a plant-based (phyto-) nutrient found in cruciferous vegetables like broccoli, cabbage, cauliflower, and Brussels sprouts. When lightly cooked or chewed, DIM is released from these foods.

We all knew that eating your broccoli was good for you. Now, you know it may have been because of DIM. Unfortunately, the quantity of veggies you’d have to eat to receive an equivalent dosage from a BioTE® DIM SGS+ supplement would make your colon explode (2 pounds of vegetables to be exact).

Sulforaphane is another phytonutrient found in the same foods as DIM. MD Anderson, one of the leading cancer institutes, promotes dietary sulforaphane for its anticancer properties. BioTE® DIM SGS+ packs sulforaphane into a concentrated form to fight cancer and frequent bowel movements (again, 2 pounds of vegetables otherwise).

For the 3rd component of BioTE® DIM SGS+, we turn to pomegranate extract. Every nutritionist loves this “superfood”.

What’s so great about pomegranates? For centuries, pomegranates have been used for a variety of health ailments. In modern times, claims have been made that pomegranates can prevent or treat:

  • Heart disease
  • Cancers (including prostate)
  • High cholesterol
  • Diabetes

Although clinical trials in humans are lacking to support these claims, basic science research at the cellular level has confirmed the anticancer and anti-inflammatory properties of pomegranates. With little downside, adding pomegranate to your diet makes sense.

Now for the tough part; getting an adequate quantity of pomegranates in your diet to gain the antioxidant benefits. For those unfamiliar with pomegranates, the nutritional value is in the red seeds. Your choices for consumption are purchasing:

  • Whole fruit (a red murder scene in your kitchen after seeding them yourself)
  • Seeds (Bill Gates can barely afford these expensive buggers)
  • Juice (too much sugar)
  • Supplements (most are of low quality)

No great options – until you consider BioTE® DIM SGS+. You’ll receive a safe, concentrated punch of pomegranate extract in a daily pill form with none of the sugar.

How does BioTE® DIM SGS+ work?

There are two main sex hormones in men and women: testosterone and estrogen. Each one is metabolized or broken down by the body into different compounds (metabolites). Let’s focus on estrogen for our BioTE DIM SGS+ discussion.

There are “healthy” ways to metabolize estrogen and “unhealthy” ways to metabolize estrogen. DIM promotes the healthy metabolism of estrogen.

For the science nerds (myself included, no judgment) the 2-hydroxy estrogens are known as the “good” estrogen metabolites. Like any good story, there are also the “bad guys” or the 16-hydroxy estrogens.

When the good guys outnumber the bad guys, our body kicks into antioxidant mode. Antioxidant is the fancy doctor term for a compound which prevents and repairs cellular DNA damage in our body. Therefore, “good” estrogen metabolites fight cancer (more to come).

Top 5 Reasons to Take BioTE® DIM SGS+

All that sounds great if you’re a science nerd, but what if you want to feel better today? What if your goal is similar to mine, and you want to live to a healthy 100 years old and have a blow-out centurion birthday party?

Here are the top 5 reasons you should start BioTE® DIM SGS+ today.

BioTE® DIM SGS+ maximizes hormone optimization

Hormone replacement therapy itself is not enough. If you think that pellets, shots, or creams alone are your fountain of youth, then you’re in for a rude awakening. This isn’t to say that hormone replacement therapy won’t make you feel better.

But we’re not interested in hormone replacement. We’re interested in hormone optimization. Maximizing the benefits of hormones for immediate and long-term health.

So, how does BioTE® DIM SGS+ optimize hormones? For the answer, we need to return to estrogen balancing (don’t worry, I’ll leave out the nerdy science details).

By promoting a more efficient estrogen metabolism, BioTE® DIM SGS+ promotes a healthy balance between testosterone and estrogen levels in men and women. If too much estrogen is left unmetabolized, then you will have lower free testosterone levels.

Lower free testosterone levels lead to weight gain and moodiness (no thanks!).

BioTE® DIM SGS+, in a sense, helps to activate testosterone by unbinding testosterone from the carrier proteins (sex-hormone binding globulin or SHBG on your lab panel). Bound testosterone is inactive. In contrast, unbound or free testosterone is like a bachelor and free to party in your organs (I mean . . . I couldn’t resist the imagery).

Higher activated testosterone and lower estrogen levels equals better hormone balancing.

Balanced hormone levels boosts your metabolism and increases fat-burning. A leaner, healthier version of yourself. Sign me up!

BioTE® DIM SGS+ protects your breasts

Nothing strikes fear in women quite like breast cancer. Breast cancer is the most commonly diagnosed cancer in U.S. women, with 1 in 8 ladies ultimately developing this disease. Similar to prostate cancer, outside of genetics and aging, there are few modifiable risk factors for breast cancer prevention.

Enter BioTE® DIM SGS+. Estrogen balance plays a vital role in the development of many breast cancers. It’s no wonder that BioTE® DIM SGS+ may help. Here’s the supporting research:

I’m suggesting BioTE® DIM SGS+ to all of my female patients concerned about future breast cancer. DIM also plays a great supporting role in preventing side effects, like breast tenderness, that is seen with hormone replacement therapy.

BioTE® DIM SGS+ protects your prostate

Prostate cancer is the most common solid organ malignancy in men, with over 240,000 men diagnosed in the U.S. each year. Other than your genetics, the main risk factor for prostate cancer development appears to be dietary. Obesity and a Western pattern diet (processed foods) have been shown to increase the risk of prostate cancer in ethnic groups who immigrate to the U.S.

Other than eating healthy, what else can you do to prevent prostate cancer? Taking BioTE® DIM SGS+ might be your answer. Basic science research in prostate cancer models has shown the following benefits to DIM:

With a paucity of tactics to otherwise mitigate a man’s risk of developing prostate cancer, this data is enough for me to recommend DIM to all my male patients. Myself included.

BioTE® DIM SGS+ boosts your immune system

Who doesn’t need a healthy immune system these days? The COVID-19 pandemic has forever changed how we view infectious diseases. With no definitive therapy, prevention with vaccinations and supporting supplements is vital.


Zinc has received the most attention, but maybe BioTE® DIM SGS+ deserves a look as well. Here’s the research to support the immune boosting properties of DIM:


Further supporting evidence for BioTE® DIM SGS+ as an immune booster is suggested in multiple cancer-model studies. One pathway for cancer formation is a dysregulated immune system. The other is excess inflammation.


Speaking of inflammation . . . 

BioTE® DIM SGS+ prevents inflammation

Inflammation is bad. Cancer, autoimmune disorders, obesity, and heart disease are only a few of the many conditions that are caused by inflammation. When your body is “jacked up” and inflamed, bad things happen.


Decreasing inflammation through healthier living should be a goal for all of us. Eating whole foods and minimizing processed foods are a great start. BioTE® DIM SGS+ can support your diet, and here’s the proof:


Incredible medical breakthroughs have been made in the treatment of diseases like Crohn’s disease and rheumatoid arthritis. Why not prevent or lessen the severity of these diseases with the addition of BioTE® DIM SGS+ to your daily routine?

Closing thoughts on BioTE® DIM SGS+

I guess mom was right when she kept telling us to “eat your broccoli!”. If healthy eating leads to healthy living, it makes sense that there had to be some magic inside all those cruciferous vegetables. Turns out that the magic was likely DIM.


Throw in the antioxidant and anti-inflammatory properties of sulforaphane and pomegranate extract, and I could argue that BioTE® DIM SGS+ may be the perfect supplement for your health.


With no reported serious side effects to BioTE® DIM SGS+ there’s little downside. Of course, stop it immediately if you notice anything out of the ordinary and contact your provider.


Your only hesitation is making certain you purchase “the real stuff”. Supplements bought over-the-counter are rarely if ever high quality. Also, BioTE® DIM SGS+ is a special formulation only sold legitimately through BioTE® providers.


If you are interested in ordering BioTE® DIM SGS+ click here and we will help you out.

Now if you’ll excuse me, I ran out of my BioTE® DIM SGS+ and decided to eat several cauliflower tacos with cabbage slaw on a high fiber tortilla. I need to find a bathroom SUPER STAT.

Dr. Joseph Pazona is a board-certified urologist practicing in Nashville, TN. He offers all forms of hormone optimization, including BioTE® pellet therapy, for men and women. He is a self-taught cook and makes delicious roasted cauliflower tacos with caramelized onions and red cabbage slaw every Monday with his wife. If you want the recipe, send him an email: hello@pazonamd.com

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About the Author

Doctor Joseph Pazona is the founder of Pazona MD, a specialty urology practice located in Nashville, TN. He has been published in medical journals on the topic of urology & authored several consumer ebooks on a variety of urologic conditions in addition to the topics of telemedicine, and continuing medical education (CME). When he’s not treating patients or writing he enjoys traveling, hiking, running, cooking, and spending time with his three children and fiancé, Catherine.


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